Francisco de la Reguera was born in Veracruz, Mexico. After finishing his studies in Visual Arts, he began his acting career in the television series Niño Santo (2011), produced by Gael García Bernal and Diego Luna. In cinema, he ventured with Hugo Lara's debut feature Cuando los hijos regresan (2017), with a role that earned him a nomination in the 2018 Canacine Awards. In addition to acting, he produced his own projects for film and theatre, and began his career as creator, writer and director with the series Los Hermanos Salvador (2022), the first Mexican fiction series released by Disney Plus, Latin America.