Chloe Castiglioni was born and raised in Milan Italy, where her passion for acting was born at the age of 8 with her local community theater. She moved to the States at the age of 14 and was very active in her high school drama club, which lead her to spend a semester at the Academy of Art University in San Francisco at the age of 16, where she attended a Pre-College Summer Program specializing in performing arts. She graduated a semester early the following year in order to move to New York City to study at the Lee Strasberg Theater and Film Institute, while working at the restaurant Eleven Madison Park to support herself and pay for her tuition.